Blar i forfatter "Sandve, Simen Rød"

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    • Diversified regulation of circadian clock gene expression following whole genome duplication 

      West, Alexander Christopher; Iversen, Marianne; Jørgensen, Even Hjalmar; Sandve, Simen Rød; Hazlerigg, David; Wood, Shona Hiedi (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-08)
      Across taxa, circadian control of physiology and behavior arises from cell-autonomous oscillations in gene expression, governed by a networks of so-called ‘clock genes’, collectively forming transcription-translation feedback loops. In modern vertebrates, these networks contain multiple copies of clock gene family members, which arose through whole genome duplication (WGD) events during evolutionary ...

    • Genome-Wide Reconstruction of Rediploidization Following Autopolyploidization across One Hundred Million Years of Salmonid Evolution 

      Gundappa, Manu Kumar; To, Thu-Hien; Grønvold, Lars; Martin, Samuel A. M.; Lien, Sigbjørn; Geist, Jürgen; Hazlerigg, David; Sandve, Simen Rød; Macqueen, Daniel J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-28)
      The long-term evolutionary impacts of whole-genome duplication (WGD) are strongly influenced by the ensuing rediploidization process. Following autopolyploidization, rediploidization involves a transition from tetraploid to diploid meiotic pairing, allowing duplicated genes (ohnologs) to diverge genetically and functionally. Our understanding of autopolyploid rediploidization has been informed ...

    • Immunologic Profiling of the Atlantic Salmon Gill by Single Nuclei Transcriptomics 

      West, Alexander Christopher; Mizoro, Yasutaka; Wood, Shona; Ince, Louise M.; Iversen, Marianne; Jørgensen, Even Hjalmar; Nome, Torfinn; Sandve, Simen Rød; Martin, Samuel A. M.; Loudon, Andrew S. I.; Hazlerigg, David (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-04)
      Anadromous salmonids begin life adapted to the freshwater environments of their natal streams before a developmental transition, known as smoltification, transforms them into marine-adapted fish. In the wild, smoltification is a photoperiod-regulated process, involving radical remodeling of gill function to cope with the profound osmotic and immunological challenges of seawater (SW) migration. While ...

    • Photoperiod-dependent developmental reprogramming of the transcriptional response to seawater entry in Atlantic salmon (Salmo salar) 

      Iversen, Marianne; Mulugeta, Teshome Dagne; West, Alexander Christopher; Jørgensen, Even Hjalmar; Martin, Samuel A. M.; Sandve, Simen Rød; Hazlerigg, David (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-12)
      The developmental transition of juvenile salmon from a freshwater resident morph (parr) to a seawater (SW) migratory morph (smolt), known as smoltification, entails a reorganization of gill function to cope with the altered water environment. Recently, we used RNAseq to characterize the breadth of transcriptional change which takes place in the gill in the FW phase of smoltification. This highlighted ...

    • RNA profiling identifies novel, photoperiodhistory dependent markers associated with enhanced saltwater performance in juvenile Atlantic salmon 

      Iversen, Marianne; Mulugeta, Teshome Dagne; Blikeng, Børge Gellein; West, Alexander Christopher; Jørgensen, Even Hjalmar; Sandve, Simen Rød; Hazlerigg, David (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-08)
      Atlantic salmon migrate to sea following completion of a developmental process known as smolting, which establishes a seawater (SW) tolerant phenotype. Smolting is stimulated by exposure to long photoperiod or continuous light (LL) following a period of exposure to short photoperiod (SP), and this leads to major changes in gill ion exchange and osmoregulatory function. Here, we performed an RNAseq ...